Shinya Yamanaka, born in 1962 in Osaka Prefecture, Japan, is a Japanese physician. He is currently the director of the iPS Cell Research Institute at Kyoto University and a professor at the University of California, San Francisco, USA. In 2012, Nobunaga Yamanaka won the Nobel Prize in Physiology or Medicine. During high school, Yamanaka was passionate about judo. He broke his bones more than 10 times due to practicing judo. Yamanaka's father told him that you had been injured multiple times. Seeing how doctors alleviate pain for patients, you will become a doctor and serve humanity in the future. In addition, Yamanaka was greatly encouraged by reading the works of physician Tokuda Huxiong, who believed that life is equal. He decided to pursue a career in medicine and was admitted to the Medical Department of National Kobe University, preparing to become an orthopedic doctor in the future. During his clinical internship after graduating from university, Yamanaka discovered that he had little talent for surgery, and even if someone else performed a 20 minute surgery, he might not have completed it in two hours; And he believes that being an excellent doctor can only help a few patients, and if medical research results are successful, it can usually help more patients, so his interest turns to basic medical research. In 2007, Masami Yamanaka discovered a method of inducing human epidermal cells to exhibit embryonic stem cell activity characteristics through experiments on mice, which earned him the 2012 Nobel Prize. This biological milestone contribution indicates that mature cells from intact mammals can be reprogrammed to induce multifunctional stem cell iPS cells, which can develop into cells from various other organs in the body. This discovery has completely changed human understanding of cell and organ growth, and textbooks have been rewritten accordingly, establishing new research fields. By reprogramming human cells, scientists have opened up new avenues for disease research and found new methods for disease treatment. Although his great discovery has excited scientists around the world and brought countless possibilities to the biomedical field, this former doctor is still very humble and cautious. We still have a lot of foundational work to do, such as ensuring the safety of iPS cells. This is not international competition in the Olympics, but international cooperation. Now, all of our work is just the beginning.
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添加时间: 山中伸弥(Shinya Yamanaka),1962年出生于日本大阪府,日本医师。现任京都大学iPS细胞研究所所长、美国加州大学旧金山分校教授。 2012年,山中信长荣获诺贝尔生理学或医学奖。高中时期,山中伸弥就热衷于柔道。他因练习柔道而骨折10余次。山中的父亲告诉他,你受过多次伤。看看医生如何为病人减轻痛苦,你将来也会成为一名医生,为人类服务。此外,山中伸弥还阅读了相信生命平等的医生德田虎雄的著作,深受鼓舞。他决定从事医学事业,并考入国立神户大学医学部,准备将来成为一名骨科医生。大学毕业后在临床实习时,山中伸弥发现自己几乎没有手术天赋,即使别人做20分钟的手术,他也不一定能在两个小时内完成;而他认为,成为一名优秀的医生只能帮助少数患者,而如果医学研究成果成功,通常可以帮助更多的患者,因此他的兴趣转向了基础医学研究。 2007年,山中正美通过小鼠实验发现了一种诱导人类表皮细胞表现出胚胎干细胞活性特征的方法,并因此获得2012年诺贝尔奖。这一生物学里程碑式的贡献表明,来自完整哺乳动物的成熟细胞可以被重新编程以诱导多功能干细胞 iPS 细胞,这些细胞可以发育成来自体内各种其他器官的细胞。这一发现彻底改变了人类对细胞和器官生长的认识,教科书也相应改写,建立了新的研究领域。通过对人类细胞进行重新编程,科学家们开辟了疾病研究的新途径,并找到了疾病治疗的新方法。尽管他的伟大发现让全世界的科学家兴奋不已,也给生物医学领域带来了无数的可能性,但这位曾经的医生仍然非常谦虚和谨慎。我们还有很多基础性工作要做,比如确保 iPS 细胞的安全性。这不是奥运会的国际竞争,而是国际合作。现在,我们所有的工作才刚刚开始。
更新时间: 2026-02-24 07:31:15
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