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John Cornforth

John Cornforth

🏆 Nobel Prize in Chemistry

Nobel Prize in Chemistry | (1953) | 1917-2013 | Australian British

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Biography

Sir John Warcup Cornforth Jr.,AC,CBE,FRS,FAA(7 September 1917 – 8 December 2013) was an Australian–British chemist who won theNobel Prize in Chemistryin 1975 for his work on thestereochemistryofenzyme-catalysedreactions,becoming the only Nobel laureate born inNew South Wales. Cornforth investigated enzymes that catalyse changes in organic compounds, the substrates, by taking the place of hydrogen atoms in a substrate's chains and rings. In his syntheses and descriptions of the structure of variousterpenes,olefins, andsteroids, Cornforth determined specifically which cluster of hydrogen atoms in a substrate were replaced by an enzyme to effect a given change in the substrate, allowing him to detail thebiosynthesisofcholesterol.For this work, he won a share of the Nobel Prize in Chemistry in 1975, alongside co-recipientVladimir Prelog, and was knighted in 1977. Fields: Organic chemistry Education: University of Sydney BSc St Catherine's College, Oxford DPhil

中文信息

简介: 诺贝尔化学奖| (1953) | 1917-2013 |澳大利亚 英国人

小约翰·沃卡普·康福斯爵士 (Sir John Warcup Cornforth Jr.),AC、CBE、FRS、FAA(1917 年 9 月 7 日至 2013 年 12 月 8 日)是一位澳大利亚裔英国化学家,因其在酶催化反应立体化学方面的工作而于 1975 年获得诺贝尔化学奖,成为唯一出生在新南威尔士州的诺贝尔奖获得者。康福斯研究了通过取代底物链和环中的氢原子来催化有机化合物(底物)变化的酶。在他对各种萜烯、烯烃和类固醇结构的合成和描述中,康福斯具体确定了底物中的哪一簇氢原子被酶取代以影响底物的给定变化,从而使他能够详细说明胆固醇的生物合成。由于这项工作,他与共同获奖者弗拉基米尔·普雷洛格 (Vladimir Prelog) 一起获得了 1975 年诺贝尔化学奖,并于 1977 年被封为爵士。悉尼大学 学士 圣凯瑟琳学院 牛津大学 哲学博士

Quick Facts

  • Award: Nobel Prize in Chemistry
  • Added: 2026-02-03
  • Source: Wikipedia